quercetin as a potential anti-allergic drug: which perspectives?

نویسندگان

salvatore chirumbolo department of pathology and diagnostics-section of general pathology, university of verona, italy

چکیده

flavonoids polyphenolic compounds that exert many anti-inflammatory and anti-microbial effects, and exhibit an anti-allergic action. quercetin is a flavonoids that recently  has  raised  many  issues  and  shown  evidence about its action as a potential drug to allergy. a chinese herbal formula, known as food allergy herbal formula (fahf) has been related with blocking of anaphylaxis to peanuts (pna) in mouse models. quercetin appears to possess the same potential of fahf as a safe anti-allergic substance but it opens only a wide perspective, at the moment, due to several complex issues that hamper the possibility to use natural medicine and phytochemicals as true drugs.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Quercetin and Its Anti-Allergic Immune Response.

Quercetin is the great representative of polyphenols, flavonoids subgroup, flavonols. Its main natural sources in foods are vegetables such as onions, the most studied quercetin containing foods, and broccoli; fruits (apples, berry crops, and grapes); some herbs; tea; and wine. Quercetin is known for its antioxidant activity in radical scavenging and anti-allergic properties characterized by st...

متن کامل

Propolis as anti-inflammatory and anti-allergic compounds: which role for flavonoids?

A recent article by Nakamura R. and colleagues has reported the effects of propolis from different geographical areas on mast cell degranulation [1]. As well as flavonoids, propolis is well known among general population for its anti-allergic properties [2,3]. Actually, propolis has plenty of biological and pharmacological properties and its mechanisms of action have been widely investigated in...

متن کامل

Chlorotoxin-conjugated onconase as a potential anti-glioma drug

Gliomas are rarely curable malignant brain tumors arising from normal glial cells. The scorpion-derived small peptide, chlorotoxin (CTX), can selectively bind malignant gliomas. In the present study, a CTX-conjugated onconase (Onc), a small cytotoxic ribonuclease, was prepared as a potential anti-glioma drug. In this conjugate, recombinant CTX was covalently linked with recombinant Onc by rever...

متن کامل

Arsenic sulfide as a potential anti-cancer drug

Arsenic sulfide (As4S4) is the main component of realgar, which is widely used in traditional Chinese medicine. Previous studies have shown the beneficial effects of As4S4 in the treatment of hematological malignant diseases, however, its effects on solid tumors have yet to be fully elucidated. The current study aimed to explore the anti‑cancer effect and the mechanism of As4S4 on solid tumors ...

متن کامل

Ellagic Acid as a Potential Anti-Cancer Drug

Cancer development and progression occurs when the cells suffers when the molecular network linking proliferation and tumor suppression gets disengaged. But this link plays a vital role in cell regulation and homeostasis. Defects in apoptosis play important roles in tumor pathogenesis, allowing neoplastic, as well as genetically unstable cells, to survive. Moreover, deregulation of apoptosis af...

متن کامل

Therapeutic Potential of Plants as Anti-microbials for Drug Discovery

The uses of traditional medicinal plants for primary health care have steadily increased worldwide in recent years. Scientists are in search of new phytochemicals that could be developed as useful anti-microbials for treatment of infectious diseases. Currently, out of 80% of pharmaceuticals derived from plants, very few are now being used as anti-microbials. Plants are rich in a wide variety of...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of allergy, asthma and immunology

جلد ۱۰، شماره ۲، صفحات ۱۳۹-۱۴۰

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023